Check out the companies making the biggest moves at noon: AppFolio — The cloud-based business software provider rose 7% after upgrading from equal weight to overweight on KeyBanc. The 12-month price target is $285, according to FactSet’s StreetAccount service. AST SpaceMobile — Shares of the space-based broadband mobile phone network fell 6% after more than doubling in the last month. According to Street Accounts, Barclays has lowered its investment rating twice from overweight to underweight, while keeping its price target at $60. Revolution Medicines — The late-stage clinical oncology company soared 10% after announcing that the Food and Drug Administration had granted vouchers for the multiselective inhibitor dalaxone lasib (RMC-6236) under the National Priority Voucher Trials Program. Dalaxone lasib is indicated for the treatment of patients with metastatic pancreatic ductal adenocarcinoma and metastatic non-small cell lung cancer. Core Scientific — The quantum computing company fell more than 5% after CoreWeave responded to a letter from investor Two Seas Capital opposing the company’s acquisition of Core Scientific. CoreWeave called its proposal “the best and final.” State Street — The asset manager fell more than 3% after reporting mixed third-quarter results. Profits and revenues exceeded expectations. Net interest income was $715 million, below FactSet’s estimate of $740.2 million. Regional Banks — The group gained after dragging the broader market lower on Thursday. Zion rebounded more than 4% following the Baird upgrade, while Western Alliance rose 2%. SPDR S&P Regional Banking ETF (KRE) rose 1%. Jefferies — The investment bank’s stock rose 4.2% after plunging more than 10% on Thursday. Oppenheimer upgraded the stock to outperform on Friday, but the firm said Jefferies’ exposure to First Brands is “very limited.” CSX — The Jacksonville, Fla.-based railroad rose 3% after third-quarter profits beat expectations. CSX reported adjusted earnings of 44 cents per share on revenue of $3.59 billion, while analysts surveyed by LSEG expected earnings of 42 cents per share and revenue of $3.58 billion. Interactive Brokers Group — Shares fell 3% after a better-than-expected third-quarter earnings report. Interactive Brokers had earnings of 57 cents per share, excluding items, on revenue of $1.61 billion. This beat LSEG’s earnings of 54 cents per share and sales of $1.52 billion. Oracle — The software stock fell 7%, giving back some of its gains in Thursday trading. Oracle confirmed its cloud computing deal with Meta on Thursday. OZK Bank — The regional bank fell 3% as its third-quarter profit fell short of expectations, widening losses seen in Thursday’s regional bank selloff. OZK Bank’s profit was $1.59 per share, below the consensus estimate of $1.66 per share among analysts surveyed by FactSet. Novo Nordisk , Eli Lilly — Pharmaceutical stocks fell 3% to 4% after President Donald Trump suggested the cost of obesity drugs could be “much lower.” However, Dr. Mehmet Oz, administrator of the Centers for Medicare and Medicaid Services, noted that the price of the popular GLP-1 drug has not yet been negotiated by the White House. Fifth Third Bancorp — Shares of the bank, which announced its acquisition of Comerica last week, rose 1% after reporting better-than-expected third-quarter earnings. Fifth Third had revenue of 91 cents per share, or $2.31 billion, compared with the forecast of 87 cents or $2.28 billion by analysts surveyed by LSEG. Comerica stock also rose 0.8% following the earnings announcement. Micron Technology — Shares fell 2% after Reuters reported, citing sources, that Micron would exit its server chip business in China. Reuters reported that Micron’s business in the Asian country failed to recover following a ban on the use of its products in critical infrastructure in 2023. American Express — The financial stock rose 6% after the company beat expectations for the third quarter and raised its full-year outlook. American Express reported profit of $18.43 billion, or $4.14 per share, for the quarter, compared with analyst estimates compiled by FactSet for profit of $18.05 billion, or $4 per share. Trust Financial — Shares rose 3.5% after the company reported better-than-expected third-quarter results. The Trust had earnings per share (excluding items) of $1.07 on revenue of $5.24 billion, compared to analysts’ expectations of $1.00 and $5.2 billion. Intuitive Machines — Space technology stocks rose 3% after Deutsche Bank upgraded the stock from hold to buy. Mr Deutsche said the risk-reward ratio of the share price was attractive and the business had commercial catalysts on the horizon. —CNBC’s Alex Harring, Fred Imbert and Pia Singh contributed reporting (Learn the best 2026 strategies from inside the NYSE with Josh Brown and more on CNBC PRO Live. Tickets and information here ).